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KMID : 1103720150720050335
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Journal of the Korean Society of Radiology
2015 Volume.72 No. 5 p.335 ~ p.343
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Comparison of the Effectiveness of Preoperative Portal Vein Embolization in Patients with Chronic Liver Disease: Gelfoam versus Gelfoam-Coil Combination
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Shin Sung-Wook
Chang Il-Soo
Joo Sung-Wook
Do Young-Soo
Park Hong-Suk
Park Kwang-Bo
Cho Sung-Ki
Choo In-Wook
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Abstract
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Purpose: To compare the effectiveness of portal vein embolization (PVE) performed using gelfoam or a gelfoam-coil combination before major hepatic resection in patients with chronic liver disease.
Materials and Methods: PVE using gelfoam or a gelfoam-coil combination was performed in 37 patients. From April 2003 to September 2007, PVE was performed using gelfoam (n = 17) and a gelfoam-coil combination (n = 20) to induce hypertrophy. Computed tomography volumetry was performed 2?4 weeks after PVE to assess the changes in liver volume.
Results: The mean percentage increase in future liver remnant volume was 23.7 ± 23.7% in the gelfoam group and 36.7 ± 18.5% in the gelfoam-coil group (p = 0.02). Recanalization was found in 15 gelfoam group patients and 8 gelfoam-coil group patients (p = 0.003). The mean tumor size increased from 4.5 ± 2.9 cm before PVE to 5.0 ± 3.5 cm after PVE in the gelfoam group and from 4.3 ± 2.2 cm before PVE to 4.7 ± 2.5 cm after PVE in the gelfoam-coil group (p = 0.80).
Conclusion: The gelfoam-coil combination was more effective than gelfoam alone for induction of compensatory hypertrophy by PVE in patients with chronic liver disease.
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KEYWORD
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Portal Vein, Embolization, Hepatocellular Carcinoma, Gelfoam, Coil
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